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1

The Positive Allosteric Modulator of α 2/3-Containing GABA A Receptors, KRM-II-81, Is Active in Pharmaco-Resistant Models of Epilepsy and Reduces Hyperexcitability after Traumatic Brain Injury

Witkin, Jeffrey M., Li, Guanguan, Golani, Lalit K., Xiong, Wenhui, Smith, Jodi L., Ping, Xingjie, Rashid, Farjana, Jahan, Rajwana, Cerne, Rok, Cook, James M., Jin, Xiaoming

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2020

File:

PDF, 1.18 MB

2020

2

GABA A receptor subtypes and the abuse-related effects of ethanol in rhesus monkeys: Experiments with selective positive allosteric modulators

Berro, Lais F., Rüedi-Bettschen, Daniela, Cook, Jemma E., Golani, Lalit K., Li, Guanguan, Jahan, Rajwana, Rashid, Farjana, Cook, James M., Rowlett, James K., Platt, Donna M.

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2019

Language:

english

File:

PDF, 631 KB

english, 2019

3

Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions Via Cellular Uptake by Folate Receptor α and the Proton-coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis

Golani, Lalit Kumar, Wallace-Povirk, Adrianne, Deis, Siobhan M., Wong, Jennifer E., Ke, Jiyuan, Gu, Xin, Raghavan, Sudhir, Wilson, Mike R., Li, Xinxin, Polin, Lisa A., de Waal, Parker W., White, Kathr

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

4

Correction to Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter

Golani, Lalit K., George, Christina, Zhao, Sai, Raghavan, Sudhir, Orr, Steven, Wallace, Adrianne, Wilson, Mike R., Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Year:

2016

File:

PDF, 378 KB

2016

5

Animal models of fatigue in major depressive disorder

Stutz, Patrick V., Golani, Lalit Kumar, Witkin, Jeffrey M.

Journal:

Physiology & Behavior

Year:

2018

Language:

english

File:

PDF, 434 KB

english, 2018

6

Improved Synthesis of Anxiolytic, Anticonvulsant, and Antinociceptive α2/α3-GABA(A)-ergic Receptor Subtype Selective Ligands as Promising Agents to Treat Anxiety, Epilepsy, and Neuropathic Pain

Li, Guanguan, Golani, Lalit, Jahan, Rajwana, Rashid, Farjana, Cook, James

Journal:

Year:

2018

Language:

english

File:

PDF, 231 KB

english, 2018

7

Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni

McCusker, Paul, Mian, Md Yeunus, Li, Guanguan, Olp, Michael D., Tiruveedhula, V. V. N. Phani Babu, Rashid, Farjana, Golani, Lalit Kumar, Verma, Ranjit S., Smith, Brian C., Cook, James M., Chan, John D

Journal:

PLoS Neglected Tropical Diseases

Year:

2019

Language:

english

File:

PDF, 5.76 MB

english, 2019

8

Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3- d ]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter

Golani, Lalit K., George, Christina, Zhao, Sai, Raghavan, Sudhir, Orr, Steven, Wallace, Adrianne, Wilson, Mike R., Hou, Zhanjun, Matherly, Larry H., Gangjee, Aleem

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 6.72 MB

english, 2014

9

The Positive Allosteric Modulator of Alpha-2/3-Containing γ-Aminobutyric Acid Type A Receptors, KRM-II-81, Is Active in Pharmacoresistant Models of Epilepsy and in Human Epileptic Tissue

Smith, Jodi L, Ping, Xingie, Jin, Xiaoming, Golani, Lalit K, Li, Guanguan, Rashid, Farjana, Jahan, Rajwana, Cook, James M, Witkin, Jeffrey M

Journal:

Year:

2019

Language:

english

File:

PDF, 101 KB

english, 2019

10

The Imidazodiazepine Anticonvulsant, KRM-II-81, Produces Novel, Non-diazepam-like Antiseizure Effects

Knutson, Daniel E., Smith, Jodi L., Ping, Xingjie, Jin, Xiaoming, Golani, Lalit K, Li, Guanguan, Tiruveedhula, V. V. N. Phani Babu, Rashid, Farjana, Mian, Md Yeunus, Jahan, Rajwana, Sharmin, Dishary,

Journal:

ACS Chemical Neuroscience

Year:

2020

File:

PDF, 1.29 MB

2020

11

Papaverine ameliorates prenatal alcoholâinduced experimental attention deficit hyperactivity disorder by regulating neuronal function, inflammation, and oxidative stress

Sharma, Niti, Dhiman, Neerupma, Golani, Lalit K, Sharma, Bhupesh

Journal:

International Journal of Developmental Neuroscience

Year:

2020

File:

PDF, 15.63 MB

2020

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